Result of psychiatric covariation

Diagnos distribution

Relative with diagnosis 91 / 644 (14%)
ADHD/ADD 121 / 644 (18%)
Asperger/PDD 297 / 644 (46%)
Low-functioning autism 17 / 644 (2%)
Other 118 / 644 (18%)

Mean age

Mean age is based on everybody that has given age for at least 3 grandfathers / grandmothers. Below 60 counts as 55, over 100 as 105, and others in the middle of the interval

Mean age is 75 years

Gender distribution

Male 273 (42%)
Female 371 (57%)

Hemochromatosis

About 0.25% of European descent has Hemochromatosis, but few knows about it (http://jama.ama-assn.org/issues/v285n17/abs/joc02264.html)

Count Own Parent Sibling Relative
Relative with diagnosis 3 1 2 2
ADHD/ADD 2 1 0 2
Asperger/PDD 7 2 1 5
Low-functioning autism 1 0 0 0
Other 6 1 1 2
Alla 19 5 4 11

% Own Parent Sibling Relative
Relative with diagnosis 3.3% 1.1% 2.2% 2.2%
ADHD/ADD 1.7% 0.8% 0.0% 1.7%
Asperger/PDD 2.4% 0.7% 0.3% 1.7%
Low-functioning autism 5.9% 0.0% 0.0% 0.0%
Other 5.1% 0.8% 0.8% 1.7%
Total 3.0% 0.8% 0.6% 1.7%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9

Cystic Fibrosis

About 0.03% of European descent has Cystic Fibrosis (http://jama.ama-assn.org/issues/v279n14/ffull/jlt0408-3.html)

Count Own Parent Sibling Relative
Relative with diagnosis 0 1 0 1
ADHD/ADD 0 1 0 2
Asperger/PDD 1 2 0 4
Low-functioning autism 0 0 1 0
Other 0 0 0 3
Alla 1 4 1 10

% Own Parent Sibling Relative
Relative with diagnosis 0.0% 1.1% 0.0% 1.1%
ADHD/ADD 0.0% 0.8% 0.0% 1.7%
Asperger/PDD 0.3% 0.7% 0.0% 1.3%
Low-functioning autism 0.0% 0.0% 5.9% 0.0%
Other 0.0% 0.0% 0.0% 2.5%
Total 0.2% 0.6% 0.2% 1.6%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9

Faktor V Leiden

About 0.1% of Europoean descent are homozygots for the Factor V Leiden mutation (http://www.mostgene.org/gd/gdvol14b.htm)

Count Own Parent Sibling Relative
Relative with diagnosis 0 0 0 0
ADHD/ADD 0 0 1 0
Asperger/PDD 7 5 1 5
Low-functioning autism 1 0 0 0
Other 0 0 1 3
Alla 8 5 3 8

% Own Parent Sibling Relative
Relative with diagnosis 0.0% 0.0% 0.0% 0.0%
ADHD/ADD 0.0% 0.0% 0.8% 0.0%
Asperger/PDD 2.4% 1.7% 0.3% 1.7%
Low-functioning autism 5.9% 0.0% 0.0% 0.0%
Other 0.0% 0.0% 0.8% 2.5%
Total 1.2% 0.8% 0.5% 1.2%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9

Huntington

Less than 0.01% of European descent gets Huntington Disease (http://www.geneclinics.org/profiles/huntington/)

Count Own Parent Sibling Relative
Relative with diagnosis 0 0 0 3
ADHD/ADD 1 1 0 1
Asperger/PDD 0 1 0 2
Low-functioning autism 0 0 1 0
Other 0 1 0 2
Alla 1 3 1 8

% Own Parent Sibling Relative
Relative with diagnosis 0.0% 0.0% 0.0% 3.3%
ADHD/ADD 0.8% 0.8% 0.0% 0.8%
Asperger/PDD 0.0% 0.3% 0.0% 0.7%
Low-functioning autism 0.0% 0.0% 5.9% 0.0%
Other 0.0% 0.8% 0.0% 1.7%
Total 0.2% 0.5% 0.2% 1.2%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9

Parkinson

0.1 to 0.2% of European and Asian descent gets Parkinson Disease (http://www.holistic-online.com/Remedies/Parkinson/pd_who-gets.htm)

Count Own Parent Sibling Relative
Relative with diagnosis 0 3 0 8
ADHD/ADD 1 3 0 15
Asperger/PDD 4 6 2 24
Low-functioning autism 1 0 0 0
Other 1 1 0 14
Alla 7 13 2 61

% Own Parent Sibling Relative
Relative with diagnosis 0.0% 3.3% 0.0% 8.8%
ADHD/ADD 0.8% 2.5% 0.0% 12.4%
Asperger/PDD 1.3% 2.0% 0.7% 8.1%
Low-functioning autism 5.9% 0.0% 0.0% 0.0%
Other 0.8% 0.8% 0.0% 11.9%
Total 1.1% 2.0% 0.3% 9.5%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9

Psoriasis

2 to 3% of European descent has Psoriasis (http://www.pharmj.com/pdf/hp/200207/hp_200207_psoriasisintro.pdf)

Count Own Parent Sibling Relative
Relative with diagnosis 7 7 2 8
ADHD/ADD 12 16 7 15
Asperger/PDD 37 39 14 23
Low-functioning autism 0 1 1 3
Other 12 10 5 13
Alla 68 73 29 62

% Own Parent Sibling Relative
Relative with diagnosis 7.7% 7.7% 2.2% 8.8%
ADHD/ADD 9.9% 13.2% 5.8% 12.4%
Asperger/PDD 12.5% 13.1% 4.7% 7.7%
Low-functioning autism 0.0% 5.9% 5.9% 17.6%
Other 10.2% 8.5% 4.2% 11.0%
Total 10.6% 11.3% 4.5% 9.6%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9

Fibromyalgia

0.5% males and 3.4% females has fibromyalgia (http://www.ucdmc.ucdavis.edu/ucdhs/health/a-z/76Fibromyalgia/doc76risk.html)

Count Own Parent Sibling Relative
Relative with diagnosis 6 5 4 4
ADHD/ADD 12 7 2 8
Asperger/PDD 26 18 8 16
Low-functioning autism 2 1 0 1
Other 9 4 4 7
Alla 55 35 18 36

% Own Parent Sibling Relative
Relative with diagnosis 6.6% 5.5% 4.4% 4.4%
ADHD/ADD 9.9% 5.8% 1.7% 6.6%
Asperger/PDD 8.8% 6.1% 2.7% 5.4%
Low-functioning autism 11.8% 5.9% 0.0% 5.9%
Other 7.6% 3.4% 3.4% 5.9%
Total 8.5% 5.4% 2.8% 5.6%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9

Multipel Sclerosis

0.1 to 0.2% has MS, which is more frequent at higher latitudes (http://www.albany.net/~tjc/genetic99.html)

Count Own Parent Sibling Relative
Relative with diagnosis 2 1 1 7
ADHD/ADD 1 3 1 4
Asperger/PDD 1 2 3 11
Low-functioning autism 0 0 1 0
Other 2 1 2 7
Alla 6 7 8 29

% Own Parent Sibling Relative
Relative with diagnosis 2.2% 1.1% 1.1% 7.7%
ADHD/ADD 0.8% 2.5% 0.8% 3.3%
Asperger/PDD 0.3% 0.7% 1.0% 3.7%
Low-functioning autism 0.0% 0.0% 5.9% 0.0%
Other 1.7% 0.8% 1.7% 5.9%
Total 0.9% 1.1% 1.2% 4.5%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9

Crooked tooth or underbite

Count Own Parent Sibling Relative
Relative with diagnosis 31 9 9 11
ADHD/ADD 35 20 12 13
Asperger/PDD 123 54 43 49
Low-functioning autism 4 2 3 3
Other 41 17 21 12
Alla 234 102 88 88

% Own Parent Sibling Relative
Relative with diagnosis 34.1% 9.9% 9.9% 12.1%
ADHD/ADD 28.9% 16.5% 9.9% 10.7%
Asperger/PDD 41.4% 18.2% 14.5% 16.5%
Low-functioning autism 23.5% 11.8% 17.6% 17.6%
Other 34.7% 14.4% 17.8% 10.2%
Total 36.3% 15.8% 13.7% 13.7%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9

Flat-footed

4% are flat-footed after 10 years of age (http://www.cps.ca/english/statements/CP/cp98-02.htm)

Count Own Parent Sibling Relative
Relative with diagnosis 23 13 4 5
ADHD/ADD 28 17 6 12
Asperger/PDD 86 60 28 32
Low-functioning autism 5 1 0 1
Other 34 16 9 10
Alla 176 107 47 60

% Own Parent Sibling Relative
Relative with diagnosis 25.3% 14.3% 4.4% 5.5%
ADHD/ADD 23.1% 14.0% 5.0% 9.9%
Asperger/PDD 29.0% 20.2% 9.4% 10.8%
Low-functioning autism 29.4% 5.9% 0.0% 5.9%
Other 28.8% 13.6% 7.6% 8.5%
Total 27.3% 16.6% 7.3% 9.3%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9

Natural red or auburn hair color

As an comparision, scots has 10% prevalence of red hair, while 40% with other hair colors are carriers. The majority who has answered the survey are of Scandinavian descent, and Scandinavians has considerably lower prevalence (http://www.aulis.com/news12.htm)

Count Own Parent Sibling Relative
Relative with diagnosis 24 16 12 19
ADHD/ADD 24 22 12 33
Asperger/PDD 70 54 27 70
Low-functioning autism 4 4 0 4
Other 31 30 11 29
Alla 153 126 62 155

% Own Parent Sibling Relative
Relative with diagnosis 26.4% 17.6% 13.2% 20.9%
ADHD/ADD 19.8% 18.2% 9.9% 27.3%
Asperger/PDD 23.6% 18.2% 9.1% 23.6%
Low-functioning autism 23.5% 23.5% 0.0% 23.5%
Other 26.3% 25.4% 9.3% 24.6%
Total 23.8% 19.6% 9.6% 24.1%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9

Freckles

Count Own Parent Sibling Relative
Relative with diagnosis 30 15 21 19
ADHD/ADD 40 35 22 23
Asperger/PDD 109 73 61 78
Low-functioning autism 5 4 1 3
Other 44 25 16 28
Alla 228 152 121 151

% Own Parent Sibling Relative
Relative with diagnosis 33.0% 16.5% 23.1% 20.9%
ADHD/ADD 33.1% 28.9% 18.2% 19.0%
Asperger/PDD 36.7% 24.6% 20.5% 26.3%
Low-functioning autism 29.4% 23.5% 5.9% 17.6%
Other 37.3% 21.2% 13.6% 23.7%
Total 35.4% 23.6% 18.8% 23.4%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9

Rhesus (RH) negative

15% of European descent are RH negative (http://www.obfocus.com/high-risk/Rh_disease/rh_diseasepr.htm)

Count Own Parent Sibling Relative
Relative with diagnosis 23 10 7 9
ADHD/ADD 20 18 2 6
Asperger/PDD 55 41 18 21
Low-functioning autism 2 2 2 1
Other 24 21 9 7
Alla 124 92 38 44

% Own Parent Sibling Relative
Relative with diagnosis 25.3% 11.0% 7.7% 9.9%
ADHD/ADD 16.5% 14.9% 1.7% 5.0%
Asperger/PDD 18.5% 13.8% 6.1% 7.1%
Low-functioning autism 11.8% 11.8% 11.8% 5.9%
Other 20.3% 17.8% 7.6% 5.9%
Total 19.3% 14.3% 5.9% 6.8%

Weighted (4 * own + 2 * parent + 2 * sibling + relative) / 9